The number of writings devoted to the philosophical and sociopolitical views of Paul Lafargue is not small. However, his literary heritage has not been published in full to this day. Nor is there a complete biography shedding light systematically on Lafargue's activity as one of the leaders of the socialist workers' movement in France, as a journalist, philosopher, and scientist. In this connection the book by Kh. N. Momdzhian is indubitably of interest. It is the most comprehensive work on Lafargue (...) in the Soviet literature. (shrink)

The release of genetically engineered organisms into the shared environment raises scientific, ethical, and societal issues. Using some form of democratic deliberation to provide the public with a voice on the policies that govern these technologies is important, but there has not been enough attention to how we should connect public deliberation to the existing regulatory process. Drawing on lessons from previous public deliberative efforts by U.S. federal agencies, we identify several practical issues that will need to be addressed if (...) relevant federal agencies are to undertake public deliberative activities to inform decision‐making about gene editing in the wild. We argue that, while agencies may have institutional capacity to undertake public deliberative activities, there may not be sufficient political support for them to do so. Advocates of public deliberation need to make a stronger case to Congress about why federal agencies should be encouraged and supported to conduct public deliberations. (shrink)

BACKGROUND: Serotonin transporter promoter genotype appears to increase risk for depression in the context of stressful life events. However, the effects of this genotype on measures of stress sensitivity are poorly understood. Therefore, this study examined whether 5-HTTLPR genotype was associated with negative information processing biases in early childhood. METHOD: Thirty-nine unselected seven-year-old children completed a negative mood induction procedure and a Self-Referent Encoding Task designed to measure positive and negative schematic processing. Children were also genotyped for the 5-HTTLPR gene. (...) RESULTS: Children who were homozygous for the short allele of the 5-HTTLPR gene showed greater negative schematic processing following a negative mood prime than those with other genotypes. 5-HTTLPR genotype was not significantly associated with positive schematic processing. LIMITATIONS: The sample size for this study was small. We did not analyze more recently reported variants of the 5-HTTLPR long alleles. CONCLUSIONS: 5-HTTLPR genotype is associated with negative information processing styles following a negative mood prime in a non-clinical sample of young children. Such cognitive styles are thought to be activated in response to stressful life events, leading to depressive symptoms; thus, cognitive styles may index the "stress-sensitivity" conferred by this genotype. (shrink)

The process of the formation of new scientific concepts conditioned by scientific and technological progress often has the consequence that many concepts formed in special sciences - such as mathematics, physics, and biology - are immediately introduced by certain authors into the sphere of philosophy.

The body of Rabbinic material that has been relied upon for the view that Pharisaism was legalistic points rather toward confidence in God's grace and toward obedience as one's appropriate response.

The strongest argument which convinced adherents of determinism put forward is that the admission of freedom of the will does away with the principle of causality within the sphere of personal existence, and makes human activity incomprehensible. “I understand” and “I explain” mean: I apprehend the presentations of experience in terms of the basic forms of thought, and in this way I assimilate them, I register them in the system of knowledge which makes up my intellectual capital. One of these (...) forms of thought, and one of the very highest importance, is the concept of causality: without it the mind would remain perpetually bemused before an orderless world of phenomena, displaying no rhyme or reason, like the world of magic or that of dreams. If, therefore, freedom of the will excludes a principle on which our intellectual well-being depends so “much, it must be rejected by the philosophical mind and given no place amongst the truths which that mind recognizes. There is a lasting validity in Immanuel Kant's observation:“If we grant that morality necessarily presupposes freedom and if at the same time we grant that speculative reason has proved that such freedom does not allow of being thought, then the former supposition— that made on behalf of morality—would have to give way to this other contention, the opposite of which involves a palpable contradiction.”. (shrink)

REALISM AND IDEALISM 1. THE CONFLICTING ELEMENTS OF THE ONTOLOGICAL QUESTION No matter what direction philosophical speculation may take, no matter how it ...

OBJECTIVES: Early-emerging, temperamental differences in fear-related traits may be a heritable vulnerability factor for anxiety disorders. Previous research indicates that the serotonin transporter promoter region polymorphism is a candidate gene for such traits. METHODS: Associations between 5-HTTLPR genotype and indices of fearful child temperament, derived from maternal report and standardized laboratory observations, were examined in a community sample of 95 preschool-aged children. RESULTS: Children with one or more long alleles of the 5-HTTLPR gene were rated as significantly more nervous during (...) standardized laboratory tasks than children who were homozygous for the short alleles. Children homozygous for the short alleles were also rated as significantly shyer, by maternal report, than those with at least one copy of the long allele of the 5-HTTLPR gene. CONCLUSIONS: This study extends the literature linking the short alleles of the serotonin transporter promoter region polymorphism to fear and anxiety-related traits in early childhood and adulthood, and is one of very few studies to examine the molecular genetics of preschoolers' temperament using multiple measures of traits in a normative sample. (shrink)

In a healthcare setting, a multitude of ethical and moral challenges are often present when patients and families direct uncivil behavior toward clinicians and staff. These negative interactions may elicit strong social and emotional reactions among staff, other patients, and visitors; and they may impede the normal functioning of an institution. Ethics Committees and Clinical Ethics Consultation Services (CECSs) can meaningfully contribute to organizational efforts to effectively manage incivility through two distinct, yet inter-related channels. First, given their responsibility to promote (...) a humane, respectful, and professional climate, many CECSs and Ethics Committees may assist institutional leadership in evaluating and monitoring incivility policies and procedures. Second, when confronted with individual incidents of patient/family incivility, Ethics Consultants can and often do work with all stakeholders to address and mitigate potentially deleterious impacts. This manuscript presents an overview of the multifaceted ethical implications of incivility in the healthcare environment, discusses the inherent qualifications of Ethics Consultants for assisting in the management of incivility, and proposes specific mitigating actions within the purview of CECSs and Ethics Committees. We also invite healthcare organizations to harness the skills and reputation of their CECSs and Ethics Committees in confronting incivility through comprehensive policies, procedures, and training. (shrink)

This book, first published in 1987, examines the notion of truth and then discusses knowledge and the way in which much of our knowledge revises or rejects the common-sense we start from. The author argues that our knowledge is not as secure as some would like to think and that there are important limits to the possibility for explanation. He shows how values permeate our ordinary thinking and argues against the objectivity of these values, showing the practical consequences of this (...) argument for teaching in schools. This stimulating approach to a fundamental educational issue does not require previous experience of formal philosophy and will be useful to both education students and teachers in schools. (shrink)